Special course
Mathematical Modeling of the Human Brain:
From Physiology to Neurodegenerative Disorders
Rome, January 15-22, 2025
Neurodegenerative diseases (NDs) are complex disorders that primarily affect the neurons in the brain and nervous system, leading to progressive deterioration and loss of function over time. A common pathological hallmark of NDs is the accumulation of disease–specific misfolded aggregated proteins in different areas of the brain (e.g., Aβ and tau in Alzheimer's disease, α–synuclein in Parkinson's disease). This course aims to discuss mathematical modeling, numerical analysis, and high-performance scientific computing to model the physiological and pathological function of the human brain and central nervous system.
Lecturers
- Prof. Paola Antonietti (Polytechnic University of Milan)
- Dr. Ivan Fumagalli (Polytechnic University of Milan)
- Prof. Nicola Mercuri (University of Rome Tor Vergata)
- Dr. Caterina Motta (University of Rome Tor Vergata)
Venue
Aula Dal Passo, SOGENE building, University of Rome Tor Vergata, via della Ricerca Scientifica 1, 00133 Rome, Italy
Program
| Wednesday, January 15 | 9:00 - 13:00 | Prof. Nicola Mercuri and Dr. Caterina Motta |
| Monday, January 20 | 14:00 - 18:00 | Prof. Paola Antonietti |
| Tuesday, January 21 | 9:00 - 13:00 | Prof. Paola Antonietti |
| Wednesday, January 22 | 9:00 - 13:00 | Dr. Ivan Fumagalli |
Prof. Mercuri and Dr. Motta will hold two lectures on Parkinson's and Alzheimer's diseases. Prof. Antonietti will discuss mathematical models and mathematical theory applied to the study of neurodegenerative diseases. Dr. Fumagalli will present some examples of applications of these models based on real data.
The lectures can be followed online via Microsoft Teams.
Links to the recordings of the lectures:
- Day 1, part 1 (by Prof. Mercuri)
- Day 1, part 2 (by Dr. Motta)
- Day 2, part 1 (by Prof. Antonietti), slides
- Day 2, part 2 (by Prof. Antonietti)
- Day 3, part 1 (by Prof. Antonietti)
- Day 4, part 1 (by Dr. Fumagalli), slides
- Day 4, part 2 (by Dr. Fumagalli)
Sponsors
The workshop is part of a series of scientific activities of the MUR Excellence Department Project MatMod@TOV (CUP E83C23000330006).